Inosinic Acid E630
nucleotide_umami — Primarily natural_or_synthetic.
Inosine-5'-monophosphate
CAS: 131-99-7
Factual Regulatory Reference
This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and is subject to change. Always refer to your local regulatory authority for the most current information.
What Is Inosinic Acid?
Inosinic acid (5'-inosinic acid, IMP) is a nucleotide flavor enhancer that, like guanylic acid (E626), synergizes powerfully with glutamates to produce intense umami taste. It is naturally abundant in meat, poultry, and fish — a key component of the umami taste of animal proteins. Commercially produced by fermentation or enzymatic hydrolysis of RNA. JECFA considers it acceptable with no ADI specified. EFSA confirmed safety. Approved globally. The combination of IMP + GMP + glutamate forms the basis of most modern savory flavor systems.
? Did You Know?
Inosinic Acid occurs naturally in Meat (especially beef and pork) and Fish (bonito, sardines). Many people consume it daily without realizing it's also a listed food additive.
Inosinic Acid isn't just a food additive — it's also used in medicine.
In the EU, Inosinic Acid has a "quantum satis" authorization — Latin for "as much as needed." This means there's no specific maximum limit; manufacturers use only what's technologically necessary.
Detailed Regulatory Assessment
United States (FDA)
Generally recognized as safe
Japan (MHLW)
Compliant with Japanese food sanitation law.
Acceptable Daily Intake (ADI)
International Standard (JECFA)
mg/kg body weight per day
European Standard (EFSA)
Everyday Perspective
For a 60kg adult, this limit is roughly equivalent to consuming:
Natural Occurrence
A nucleotide that provides intense umami flavor, naturally found in meat and fish. Forms synergistically with glutamates to multiply savory taste.
Manufacturing
Produced by enzymatic degradation of RNA from yeast or bacteria.
Applications Beyond Food
Nutritional supplement