Calcium 5'-Ribonucleotides E634
nucleotide_umami — Primarily synthetic.
Calcium 5'-ribonucleotides
CAS: 5550-12-9 / 6106-04-3
Factual Regulatory Reference
This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and is subject to change. Always refer to your local regulatory authority for the most current information.
What Is Calcium 5'-Ribonucleotides?
Calcium 5'-ribonucleotides is a calcium salt mixture of 5'-guanylate and 5'-inosinate, used as a flavor enhancer providing the combined nucleotide synergy of both GMP and IMP. Used in processed foods and seasonings. JECFA considers it acceptable with no ADI specified. EFSA confirmed safety in its nucleotide flavor enhancer review. Approved in the EU and other jurisdictions. The mixed ribonucleotide salts provide a convenient single-ingredient approach to delivering both IMP and GMP for umami flavor enhancement.
? Did You Know?
In the EU, Calcium 5'-Ribonucleotides has a "quantum satis" authorization — Latin for "as much as needed." This means there's no specific maximum limit; manufacturers use only what's technologically necessary.
Detailed Regulatory Assessment
United States (FDA)
Generally recognized as safe
Japan (MHLW)
Compliant with Japanese food sanitation law.
Acceptable Daily Intake (ADI)
International Standard (JECFA)
mg/kg body weight per day
European Standard (EFSA)
Everyday Perspective
For a 60kg adult, this limit is roughly equivalent to consuming:
Natural Occurrence
This additive is not known to occur naturally in significant quantities.
Manufacturing
Produced by blending calcium inosinate and calcium guanylate.