Disclaimer: This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and may change. Always refer to your local regulatory authority for the most current information.
Cyclamate
E952 | INS 952
Names & Identifiers
- E Number
- E952
- INS Number
- 952
- CAS Number
- 139-05-9
- Scientific Name
- Sodium cyclohexylsulfamate
- Japanese Name
- シクラミン酸
- Also Known As
- Sodium cyclamate, Cyclamic acid, Sucaryl
Regulation Status by Country
European Union
Status: approved | Max level: varies by food category mg/kg
Maximum levels typically 250-1600 mg/kg
View EFSA Opinion →United States
Status: banned
Banned since 1969 due to bladder cancer concerns in animal studies
Japan
Status: banned
Not approved for use in foods
Australia / New Zealand
Status: approved | Code: 952
Canada
Status: approved
What is Cyclamate?
Classification
Function: sweetener
Type: artificial
Source: synthetic
How It's Made
Method: chemical synthesis
Produced by sulfonation of cyclohexylamine followed by neutralization with sodium hydroxide.
Uses Beyond Food
- Pharmaceutical: Used in some countries in pharmaceutical preparations.
Commonly Found In
Cyclamate is typically used in:
Note: This list shows typical product categories and may vary by brand and region. Always check product labels for actual ingredients.
Safety Evaluations (Official)
ADI = Acceptable Daily Intake (mg per kg of body weight per day)
ADI in Everyday Terms
For a 60 kg adult, the JECFA ADI of 7 mg/kg bw/day equals approximately 420 mg per day.
This is roughly equivalent to:
- ~2 cans of diet beverage (355ml, in EU/Canada) (typical: ~250 mg per serving)
- ~14 packets of tabletop sweetener (typical: ~30 mg per serving)
Research & Official Documents
Official evaluations and scientific research:
Search research databases:
Regulatory History
View Full Timeline →Key regulatory events and safety evaluations over time.
Cyclamate discovered accidentally by graduate student Michael Sveda at University of Illinois.
FDA approved cyclamate as GRAS (Generally Recognized As Safe) sweetener.
Studies suggested that cyclamate combined with saccharin may cause bladder cancer in laboratory rats.
FDA banned cyclamate in the USA under Delaney Clause due to cancer concerns in animal studies.
JECFA established ADI of 0-11 mg/kg bw/day, concluded cyclamate is safe at this level.
Cyclamate approved as E952 in the EU with maximum use levels specified.
Scientific Committee on Food re-evaluated cyclamate, confirmed ADI of 7 mg/kg bw/day (lower than JECFA).
EFSA re-evaluated cyclamate and cyclamic acid (E952), maintained previous safety conclusions and ADI.
Cyclamate remains banned in USA despite multiple petitions for re-approval and approval in many other countries.
Frequently Asked Questions
What is Cyclamate (E952)?
Cyclamate (E952) is a sweetener used in food products. It is artificial and synthetic. A synthetic non-caloric sweetener approximately 30-50 times sweeter than sucrose.
Is Cyclamate banned in any country?
Cyclamate is banned in USA, Japan. Regulatory status varies by country. Always check with your local food regulatory authority for current information.
What is the ADI for Cyclamate?
The Acceptable Daily Intake (ADI) for Cyclamate is 0–11 mg/kg bw/day as established by JECFA (Joint FAO/WHO Expert Committee on Food Additives). ADI represents the amount that can be consumed daily over a lifetime without appreciable health risk.
What foods contain Cyclamate?
Cyclamate is used in various food categories including Other non-alcoholic beverages, Other confectionery. It is used as a sweetener in these products.
Is Cyclamate the same as Sodium cyclamate?
Yes, Cyclamate is also known as Sodium cyclamate, Cyclamic acid, Sucaryl. These are different names for the same substance.
Related Additives
Other sweeteners in our database: