Food Additive DB

Cross-Country Regulation Comparison

Disclaimer: This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and may change. Always refer to your local regulatory authority for the most current information.

Regulatory History: Tartrazine

E102 — Complete timeline of regulatory events

About This Timeline

This page documents the regulatory history of Tartrazine (E102), including approvals, bans, safety evaluations, and classification changes by regulatory agencies worldwide.

Data source: Official regulatory documents, scientific publications, and agency announcements. All events are documented with source agencies and dates.

Complete Timeline

8 events
1916 approved
FDA • USA

Tartrazine approved for use in foods in the USA.

1959 listed
FDA • USA

Tartrazine listed as certified color additive FD&C Yellow No. 5 under Color Additives Amendment.

1979 labeling requirement
FDA • USA

FDA required specific labeling of tartrazine due to reports of allergic reactions in sensitive individuals, particularly those with aspirin sensitivity.

Sep 2007 publication
University of Southampton • UK

Southampton study published in The Lancet suggesting link between artificial colors (including tartrazine) and hyperactivity in children.

2008 reviewed
EFSA • EU

EFSA reviewed Southampton study, concluded evidence does not warrant revision of ADI but noted some children may show sensitivity.

Jul 2010 labeling requirement
European Commission • EU

EU mandated warning label on foods containing tartrazine and other azo dyes: 'may have an adverse effect on activity and attention in children'.

2014 re-evaluated
EFSA • EU

EFSA re-evaluated tartrazine (E102), reduced ADI from 7.5 to 7.5 mg/kg bw/day after comprehensive review of toxicological data.

2021 proposed legislation
California EPA • USA

California Assembly Bill introduced to ban tartrazine and other synthetic dyes in foods (not enacted).

Important Notes

  • This timeline is for informational purposes only and does not constitute safety advice.
  • Regulatory decisions reflect the state of scientific knowledge at the time they were made.
  • Current regulations may differ from historical events shown. Always consult official sources for up-to-date information.
  • An approval in one country does not imply approval in others. Regulatory standards vary by jurisdiction.