Disclaimer: This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and may change. Always refer to your local regulatory authority for the most current information.
Regulatory History: Titanium Dioxide
E171 — Complete timeline of regulatory events
About This Timeline
This page documents the regulatory history of Titanium Dioxide (E171), including approvals, bans, safety evaluations, and classification changes by regulatory agencies worldwide.
Data source: Official regulatory documents, scientific publications, and agency announcements. All events are documented with source agencies and dates.
Complete Timeline
8 eventsFDA approved titanium dioxide for use in food, not to exceed 1% of food weight.
Food-grade titanium dioxide authorized in the EU under E171 designation.
EFSA re-evaluated E171, identified data gaps on particle size distribution and possible effects on reproductive system. Recommended new studies.
France suspended use of E171 in food products, ahead of EU-wide action, citing precautionary principle.
EFSA concluded E171 can no longer be considered safe as a food additive. Genotoxicity concerns could not be ruled out after reviewing evidence on nanoparticles.
Commission Regulation (EU) 2022/63 published, removing E171 from permitted additives list (Annexes II and III). Six-month transition period announced.
Full ban on E171 as food additive in EU entered into force.
EU Court of Justice ruling confirmed that titanium dioxide powder forms are no longer classified as suspected carcinogen by inhalation, but food ban remains.
Important Notes
- This timeline is for informational purposes only and does not constitute safety advice.
- Regulatory decisions reflect the state of scientific knowledge at the time they were made.
- Current regulations may differ from historical events shown. Always consult official sources for up-to-date information.
- An approval in one country does not imply approval in others. Regulatory standards vary by jurisdiction.