Disclaimer: This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and may change. Always refer to your local regulatory authority for the most current information.
Regulatory History: Aspartame
E951 — Complete timeline of regulatory events
About This Timeline
This page documents the regulatory history of Aspartame (E951), including approvals, bans, safety evaluations, and classification changes by regulatory agencies worldwide.
Data source: Official regulatory documents, scientific publications, and agency announcements. All events are documented with source agencies and dates.
Complete Timeline
10 eventsAspartame discovered accidentally by chemist James M. Schlatter while developing anti-ulcer drug.
FDA initially approved aspartame for limited uses, but approval was stayed pending further review.
FDA approved aspartame for dry goods and tabletop sweetener use.
FDA approved aspartame for use in carbonated beverages.
FDA approved aspartame as a general purpose sweetener for all foods and beverages.
EFSA Scientific Committee on Food confirmed safety and ADI of 40 mg/kg bw/day.
EFSA completed comprehensive risk assessment, concluded aspartame and its breakdown products are safe at current exposure levels. Confirmed ADI of 40 mg/kg bw/day.
IARC classified aspartame as 'possibly carcinogenic to humans' (Group 2B) based on limited evidence.
JECFA (meeting same month as IARC) reaffirmed ADI of 0-40 mg/kg bw/day, concluded no reason to change previously established safe intake levels.
WHO and EFSA clarified that aspartame remains safe at current exposure levels despite IARC Group 2B classification. IARC identifies hazard, not risk at typical consumption.
Important Notes
- This timeline is for informational purposes only and does not constitute safety advice.
- Regulatory decisions reflect the state of scientific knowledge at the time they were made.
- Current regulations may differ from historical events shown. Always consult official sources for up-to-date information.
- An approval in one country does not imply approval in others. Regulatory standards vary by jurisdiction.